ID # 77761Date of Inclusion: 01/04/2015 Last Activities: 19/04/2017
Parkinson Institute Biobank
Parkinson Institute Biobank The main aim of the Parkinson Institute's Biobank, directed by dr. Stefano Goldwurm, is to collect and store DNA samples, as well as RNA, serum, cell lines and post-mortem nervous tissues (BrainBank), from patients affected by movement disorders attending the Institute (http://www.parkinsonbiobank.com/). The Parkinson Institute located in the Hospital – ASST “Pini-CTO” (formerly Istituti Clinici di Perfezionamento- ICP) in Milan, Italy directed by Professor Gianni Pezzoli is a specialized referral centre that operates in the field of movement disorders and that represents the ideal place where to start a DNA Bank for PD, allowing the collection of many samples from patients assessed and followed up according to homogeneous and highly specialized standards. All patients are fully characterized in terms of medical history, clinical findings, and any other relevant information and undergo detailed follow-up by a highly specialised team who resort to the most advanced diagnostic techniques and therapeutic measures available. All clinical and personal data are collected in full electronic medical records and in specific databases available to researchers. In addition to patients, controls not affected by neurodegenerative disease are also collected, usually among partners/caregivers (1500 entries). This enables us to collect a large group of healthy controls matched by ethnic and regional origin and by age. Since 2003, the Biobank is funded by the Italian Telethon Foundation as part of the Telethon Genetic Biobank Network (http://biobanknetwork.telethon.it/) and is revised by an international scientific committee yearly. All patients who participate to the Biobank are routinely analysed for the major PD genes.